The following Cyclin D2 ELISA kits are useful research tools for the measurement of cyclin D2 in biological samples. In humans this protein is encoded by the CCND2 gene. This protein is a reported regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. The canonical protein structure is reported to have an amino acid length of 289 residues, a mass of 33.1 kDa, and is a member of the Cyclin protein family. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome. This protein may also be known as MPPH3, G1/S-specific cyclin-D2, and KIAK0002.
The detection range for different cyclin D2 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.